Why Patients Need You
Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.
What You Will Achieve
As a Senior Associate Scientist, you will be at the center of our operations and you'll find that everything we do, every day, is in line with an unwavering commitment to quality. Your significant experience of applying knowledge of principles, concepts, and practices of the discipline will make you a critical member of the team. This laboratory-based position is in the Analytical Development group within Vaccine Research and Development. The primary function of this role is to develop analytical assays in support of the extensive vaccine portfolio. You will collaborate closely with scientists across the Early BioProcess Development (EBPD) to design and implement testing approaches for RNA product expression and potency of novel adjuvants. You will participate in regular vaccine development meetings and represent the group on multidisciplinary teams.
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How You Will Achieve It
- Contribute to achievement of immediate work group goals and collaborate with other team members.
- Assist in the maintenance and renewal of laboratory instruments, systems or apparatus, and in the maintenance and continuous improvement of safe and effective working practices.
- Perform in-vitro expression analysis of mRNA Drug Substance (DS) and Drug Products (DP) for multiple RNA vaccine programs.
- Provide laboratory-based support for assay development, including ELISA and cell-based assays to support adjuvant development.
- Support sample testing for process development, formulation development, critical reagents characterization and on-going stability studies.
- Analyze data using appropriate statistical software, such as GraphPad Prism
- Document experiments, data, and conclusions in an electronic lab notebook (ELN) contemporaneously.
- Contribute to authoring technical documents, including development reports, analytical lab methods, and method qualification reports.
- Review scientific and technical literature to stay current in the field.
- Present data in meetings within the department.
Qualifications
Must-Have
- Bachelor's degree in biological science, microbiology, immunology, or related fields with 3+ years relevant laboratory experience.
- Strong background and experience in mammalian cell culture, DNA and RNA transfection, and reporter cell assays.
- Experience with ELISA assay.
- Experience with in vitro expression and flow cytometry.
- Knowledge of innate and acquired immunity, with the ability to apply this knowledge to test novel adjuvants.
- Proficiency in analytical software, including GraphPad Prism and SoftMax.
- Proficiency in computer skills including Microsoft Word, PowerPoint, and Excel.
- Interact effectively with peers and leaders as part of a multidisciplinary team.
- Effective verbal and written communication skills.
Nice-to-Have
- Experience with authoring development reports and lab methods.
- Experience in documenting experiments using Signals electronic lab notebook.
PHYSICAL/MENTAL REQUIREMENTS
- Ability to work 40 hours/week in a laboratory setting
- Ability to perform data analysis
Other Job Details:
- Last Date to Apply: November 11, 2024.
- Geography includes: USA - NY - Pearl River
- Eligible for Relocation Package - NO
- Work Location Assignment: On Premise
The annual base salary for this position ranges from $64 600,00 to $107 600,00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 7,5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
Relocation assistance may be available based on business needs and/or eligibility.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Research and Development
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