Summary
Location: Basel, Switzerland
Role Purpose:
We have a fantastic opportunity for a Oligonucleotide Chemist in our CHAD department here in Basel.
About the Role
Your responsibilities include, but are not limited to:
- Defining fit-for-purpose synthesis strategy for drug substance manufacturing and Health Authority documentation.
- Develop efficient and scalable oligonucleotide processes on relevant projects within Novartis portfolio across different scales.
- Be part of the Oligo chemist / engineering team to develop and optimize syntheses used in process R&D.
- Investigate various approaches for oligonucleotide synthesis and evaluate their potential by applying cutting-edge automated platforms.
- Ensuring utilization of state-of-the-art technologies and science.
- Efficient use of lab resources.
- Maintaining oversight on process safety.
- Co-leading the process transfer to pilot plants.
- Serving as consultants for troubleshooting during campaigns.
- Collaborating with internal and external stakeholders or partners
- Collaborate with diverse experts in the areas of Nucleic Acid Chemisty, Process Chemistry, Process Engineering and Analytics.
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What you'll bring to the role:
- A completed PhD in Organic Chemistry,
- PostDoc with a focus on oligonucleotides synthesis.
- Experience in developing platform synthesis concepts for oligonucleotides
- Experience in process development using state of art oligo synthesizers.
- Experience in downstream processing including TFF and chromatographic processes
- An excellent track record of original research and extensive experience in using "state of the art" technologies.
- Fluency in English.
Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.
Accessibility and accommodation
Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message.
Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients' lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture
Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network
Benefits and Rewards: Read our handbook to learn about all the ways we'll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards
Division
Development
Business Unit
Innovative Medicines
Location
Switzerland
Site
Basel (City)
Company / Legal Entity
C028 (FCRS = CH028) Novartis Pharma AG
Functional Area
Research & Development
Job Type
Full time
Employment Type
Regular
Shift Work
No