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Associate Principal Scientist, Quantitative Biosciences

AT Merck
Merck

Associate Principal Scientist, Quantitative Biosciences

Spring House, PA

Job Description

Job Description:

At our company, we are committed to improving the health and well-being of people around the world. As a leading global pharmaceutical company, we strive to make a difference through innovative research, discovery, and development of life-saving medications and vaccines. With over a century of experience and a steadfast dedication to scientific excellence, we have become a trusted name in the industry. Join our team and be a part of our mission to create a healthier future for all.

We have an exciting opportunity for an Associate Principal Scientist with significant experience in immunological assays and drug discovery to join our Quantitative Biosciences team in West Point, PA. Working collaboratively with our local discovery teams the successful candidate will apply their skills in immunological assay development, data analysis, laboratory automation and assay detection technologies such as high content imaging and flow cytometry to advance therapeutic programs in Immunology, Neuroscience and Infectious Diseases/Vaccines. If you are lab-focused, energetic, and looking to further develop your career in pharmacology and drug discovery, we'd love for you to be part of our diverse and passionate team.

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In this role you will:

  • Develop and execute novel, creative, and translatable assays, critically analyze and interpret the data from these assays, and integrate the data with results generated in other functional areas to ensure success of discovery programs in Immunology, Neuroscience and Infectious Diseases/Vaccines.
  • Represent Quantitative Biosciences on core discovery program teams as needed and partner across these matrixed program teams to define program strategy and goals and to coordinate department engagement to deliver on those goals.
  • Collaborate with our disease area, genome sciences and chemical biology colleagues as needed to identify our next generation of drug targets.
  • Identify, validate, and integrate new technologies or methodologies to increase efficiency and productivity, drive program progression, and facilitate clinical translation of discovery programs.
  • Work with automation engineers to transfer assays developed at the bench onto integrated robotic systems.
  • Provide guidance and mentorship to less experienced scientists, empowering their success and ensuring their professional development.
  • Properly document protocols and findings, author preclinical regulatory documents, and comply with all laboratory safety requirements.
  • Integrate and interpret complex data and communicate science and strategy to stakeholders and management.

What you will need:

  • An advanced degree in Immunology, pharmacology, or a related discipline, and a BS degree with 12+ years relevant experience, or an MS degree with 8+ years relevant experience, or a Ph.D. with 4+ years relevant experience.
  • A proven track record in the design and execution of cell based and/or ex vivo immunological assays to support drug discovery efforts using detection technologies such as fluorescence/luminescence, flow cytometry, high content imaging, ELISA, Mesoscale/ Luminex.
  • A robust understanding of drug discovery and clinical development and experience on drug discovery programs from at least lead identification through to the delivery of a preclinical candidate.
  • An ability to provide mentorship and guidance to more junior scientists and peers.
  • An expert knowledge of immunology, and preferably an additional working knowledge of neuroscience and/or infectious diseases/vaccines.
  • Knowledge and experience using automated liquid handlers for incorporation into assay development.
  • The ability to communicate effectively with and relate to a broad range of stakeholders, including senior leaders, peers, direct reports, partner organizations and external collaborators.
  • Excellent written and oral communication skills.
  • The ability to adapt to changing priorities.
  • A passion for innovation and problem-solving.

NOTICE FOR INTERNAL APPLICANTS

In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.

If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.

#EligibleforERP #EBRG #vet

Current Employees apply HERE

Current Contingent Workers apply HERE

US and Puerto Rico Residents Only:

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

EEOC Know Your Rights

EEOC GINA Supplement

Pay Transparency Nondiscrimination

We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively.

Learn more about your rights, including under California, Colorado and other US State Acts

U.S. Hybrid Work Model

Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as "remote".

San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles' Fair Chance Initiative for Hiring Ordinance

Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status:
Regular

Relocation:
Domestic

VISA Sponsorship:
Yes

Travel Requirements:
10%

Flexible Work Arrangements:
Not Applicable

Shift:
1st - Day

Valid Driving License:
No

Hazardous Material(s):
viruses, radioactive materials

Job Posting End Date:
11/6/2024
*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Requisition ID:R316244

Client-provided location(s): West Point, PA, USA
Job ID: Merck-517763125
Employment Type: Full Time