Job title: Postdoctoral Researcher Upstream Cellular Biology
Hiring Manager: Victor Cairns
Location:Framingham. MA
About the Job
Are you ready to shape the future of medicine? The race is on to speed up drug discovery and development to find answers for patients and their families. Your skills could be critical in helping our teams accelerate progress.
We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people's lives. We're also a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started?
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Main Responsibilities:
- The successful applicant will play a key role in generation of Sanofi's next generation expression platform for production of protein biologics involving generation of CHO cell lines stably expressing candidate biotherapeutics via recombinase mediated integration of transgenes
- Perform genetic and phenotypic characterization of CHO cell lines, including transgene copy number and transcript analysis, cell growth, and protein production
- Execute various molecular techniques for assembly of expression vectors, including Gibson assembly Gateway, PCR, restriction endonuclease digestions, DNA plasmid preparations, etc.
- Use of basic sequence analysis tools (BLAST, Geneious, etc.) to analyse vector and genomic nucleotide sequences
- Prepare reports, presentations, and publications to effectively communicate plans, progress, and results.
About You
At this time, Sanofi will not sponsor a new applicant for employment authorization or offer any immigration related support for this position (i.e. H1B, F-1 OPT, F-1 STEM OPT, F-1 CPT, J-1, TN, or another type of work authorization).
Basic Qualifications:
- PhD in Biology, Molecular Biology or related field (+0-3 years experience)
- Experience with complex vector construction strategy (i.e. Gibson/Infusion assembly, Gateway) and molecular biology techniques.
- Self-motivated with excellent attention to detail and superb organizational skills.
- The ability to work within a fast-paced environment.
Preferred Qualifications:
- Experience with mammalian cell culture techniques, Experience with automation (Hamilton/tecan/etc).
- Aseptic technique, cell counting, passaging, cryopreservation, transfection, Gibson assembly, PCR, DNA/RNA isolation, ddPCR
- Bring the miracles of science to life alongside a supportive, future-focused team.
- Discover endless opportunities to grow your talent and drive your career, whether it's through a promotion or lateral move, at home or internationally.
- Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
- Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks' gender-neutral parental leave.
Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.
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