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2025 Spring Co-Op GMU CMC Purification Process Development

AT Sanofi U.S.
Sanofi U.S.

2025 Spring Co-Op GMU CMC Purification Process Development

Gunnison, CO

Genomic Medicine Purification Process Development Co-Op, Waltham, MA

About the job

We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people's lives. We're also a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started?

Position Overview/Department Description:

The Genomic Medicine Unit (GMU) Chemistry, Manufacturing and Control (CMC) group at Sanofi is dedicated to the establishment of best-in-class manufacturing platforms to support development of life-changing advanced cell and gene therapy products, including recombinant Adeno-associated viral vectors (AAV), non-viral and cell therapy products. This 6-month position centers on drug substance process development for gene therapy but will interface with a broader team of vector and cell line engineering, upstream process development, analytics, and clinical manufacturing support.

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A successful candidate in this role will be engaged in actively learning new techniques, independently performing experiments, analyzing and presenting results, and collaborating with different functions to understand the cross-functional nature of decision-making. Project topic will be commensurate with level of previous experience.

At this time, Sanofi will not sponsor a new applicant for employment authorization, or offer any immigration related support for this position (i.e. H1B, F-1 OPT, F-1 STEM OPT, F-1 CPT, J-1, TN, or another type of work authorization).

Key Responsibilities:
  • Design and execute viral vector purification experiments.
  • Perform analytical characterization of samples and analyze results.
  • Work with cross-functional team for feedback and present findings.
  • Contribute to technical reports and/or external publications if appropriate to project topic and level of experience.

Basic Qualifications:
  • Currently pursuing a PhD, MS, or BS degree in chemistry, chemical engineering, or biological engineering with relevant study experience.
  • Must be enrolled in school the semester following your internship/co-op with Sanofi.
  • Must be able to work in a hybrid work environment in our Waltham, MA office for the duration of the co-op
  • Must have permanent US work authorization
  • Understanding of drug substance purification process concepts.
  • Theoretical and practical knowledge of mass transfer and fluid dynamics.
  • Knowledge and understanding of technologies and operations such as:
    • Chromatography, tangential flow filtration, normal flow filtration, and/or viral clearance and inactivation
    • Advanced analytical tools to characterize particles and viral vectors

  • Work under minimal supervision and function within a collaborative, team-oriented environment.
  • Ability to work in Biosafety Level 2, follow safe lab procedures, and maintain good laboratory practices (GLPs) including detail-oriented laboratory notebook documentation.

Preferred Qualifications:
  • Experience with viral vector purification and characterization.
  • Experience with SEC-HPLC, DLS, ddPCR/qPCR, Western blot, ELISA, spectroscopic and bioassay techniques.
  • Experience with AKTA chromatography and filtration instruments.
  • Experience with protein characterization such as NanoSight 3000, Caliper LabChip GXII, Multi-Angle LS (MALS), or similar instruments.
  • Basic understanding of the principles of Quality by Design and ability to apply DOE to downstream development.
  • Excellent communication skills and ability to build cross-functional relationships.
  • Experience in protein characterization, high-throughput, engineering and data analysis, analytical techniques, and/or viral vector purification is preferred.

Why Choose Us

  • Bring the miracles of science to life alongside a supportive, future-focused team.

  • Discover endless opportunities to grow your talent and drive your career, whether it's through a promotion or lateral move, at home or internationally.

  • Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

  • Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks' gender-neutral parental leave.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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Client-provided location(s): United States
Job ID: Sanofi-https://jobs.sanofi.com/en/job/waltham/2025-spring-co-op-gmu-cmc-purification-process-development/2649/16422205760
Employment Type: Intern