Responsibilities:

• Conduct experimental research to investigate the growth, differentiation, and metabolic support of OPCs, as well as their myelination potential in the developing CNS (central nervous system).
• Utilize single-cell RNA sequencing (scRNAseq) and spatial transcriptomics data from iPSCs-derived translational models to identify disease-associated oligodendrocytes (DOLs) markers.
• Develop and maintain long-term in vitro models of OPCs differentiation from human pluripotent stem cells (iPSCs) that mimic in vivo conditions.
• Collaborate with a multidisciplinary team to design and execute experiments.
• Analyze and interpret data and contributing to scientific publications and presentations.
• Present research findings at conferences and scientific meetings.

Minimum education required:

• Ph.D. in a relevant field such as stem cell biology, neurobiology, or a related discipline expected by May 1, 2025.

Required experience skills:

• Strong background in cell culture techniques, iPSC differentiation, and molecular biology.
• Experience with single-cell RNA sequencing and bioinformatics analysis is highly desirable.
• Experience in CNS or neurology or related field.
• Demonstrated skills in experimental design, data analysis, and interpretation.
• Excellent written and oral communication skills.
• Ability to work independently and collaboratively in a team setting.
• Track record of scientific publications is advantageous.

We offer:

• A stimulating and supportive research environment with state-of-the-art facilities
• Access to a multidisciplinary team comprised of experienced researchers and machine learning engineers.
• Opportunities for career development, mentorship, and training.
• Competitive salary and benefits package.
• Application: Applicants should submit a cover letter outlining their research experience and interests, a detailed curriculum vitae (CV), a list of publications, and contact information for three references.

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In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.

If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.

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U.S. Hybrid Work Model

Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as "remote".

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Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status:
Regular

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Job Posting End Date:
11/15/2024
*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Requisition ID:R316450