The Senior Principal Scientist / Senior Manager, Cell Therapy Vector Biology position in the Cell Therapy Platform & Discovery group of Therapeutics Discovery offers an exciting opportunity to help develop novel Cell & Gene Therapies for unmet medical needs. We are investigating the use of engineered lentiviral vectors (LVV) for ex vivo and in vivo gene delivery to T cells to treat cancer. We are seeking a highly motivated researcher to lead a Vector Engineering effort with a focus on novel discovery programs. Do you have industry experience with LVV engineering and the ability to lead an enthusiastic team? Come join us in our mission to build the next generation of Cell & Gene Therapies for Oncology.

Primary responsibilities:

• Lead the Cell Therapy Vector Biology team, including vector biology, analytics, and plasmid & vector core

• Design/implement novel LVV pseudotyping screens to engineer cell-specific gene delivery vectors

• Design/implement analytical assays to characterize viral vectors

• Stay ahead of the viral vector engineering field by exploring new technologies, including high-throughput platforms and concepts.

• Execute research timelines to meet program and corporate objectives and deliver quality data

• Oversee plasmid and viral generation (lentivirus and retrovirus) to deliver high quality vectors supporting multiple cell therapy programs in a timely manner

• Contribute to a collaborative, creative, and rigorous culture of scientific discovery

Qualifications

• Ph.D. in Virology, Gene Therapy, Cell Biology, Molecular Biology, or related field with 2+ years of experience in the biotech/pharmaceutical industry; OR BS or MS with 8+ years of related experience is required.
• Expertise in LVV engineering and viral vector analytical methods is required
• Expertise in molecular biology, including plasmid cloning, scale-up, sequencing, and QC, is required
• Experience managing people is required and experience managing small teams responsible for supporting multiple project teams is preferred
• Strong critical, scientific, and strategic thinking skills are required
• Strong organizational skills, with the ability to manage multiple projects in parallel and meet timelines, are required
• Demonstrated ability to work collaboratively in cross-functional teams is required
• Experience working with high throughput automation is preferred
• This role may require up to 25% travel.

The anticipated base pay range for this position is 137000 to 235750.

The Company maintains highly competitive, performance-based compensation programs. Under current guidelines, this position is eligible for an annual performance bonus in accordance with the terms of the applicable plan. The annual performance bonus is a cash bonus intended to provide an incentive to achieve annual targeted results by rewarding for individual and the corporation's performance over a calendar/performance year. Bonuses are awarded at the Company's discretion on an individual basis.

Employees and/or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance.

• Employees may be eligible to participate in the Company's consolidated retirement plan (pension) and savings plan (401(k)).
• This position is eligible to participate in the Company's long-term incentive program.
• Employees are eligible for the following time off benefits:
• Vacation - up to 120 hours per calendar year
• Sick time - up to 40 hours per calendar year; for employees who reside in the State of Washington - up to 56 hours per calendar year
• Holiday pay, including Floating Holidays - up to 13 days per calendar year of Work, Personal and Family Time - up to 40 hours per calendar year
• Additional information can be found through the link below. https://www.careers.jnj.com/employee-benefits

The compensation and benefits information set forth in this posting applies to candidates hired in the United States. Candidates hired outside the United States will be eligible for compensation and benefits in accordance with their local market."

Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

For more information on how we support the whole health of our employees throughout their wellness, career and life journey, please visit www.careers.jnj.com.