Johnson & Johnson is recruiting for a Senior Scientist, Protein Characterization by Mass Spectrometry located in Malvern, PA.
At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com/.
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The Therapeutics Discovery & Supply-Analytical Development (TDS-AD) is recruiting for a Senior Scientist located in Malvern, PA. We discover and develop creative large molecule solutions to address significant unmet medical needs in oncology, immunology, neuroscience, infectious diseases and vaccines, and cardiovascular and metabolic diseases.
The Analytical Development organization is continuing to build key scientific expertise in protein and vaccine characterization, and primary structure elucidation! We need a hardworking scientist willing to bring their expertise to exciting efforts in novel areas of protein characterization.
You will join the Primary Structure team within the Characterization group in the TDS-AD department to conduct product characterization and process development activities.
Key Responsibilities:
- Operate state-of-the-art LC and MS instrumentation
- Learn and apply different software packages for LCMS/protein analysis
- Perform LCMS-based quantitation of post-translational modifications
- Design and implement peptide mapping / MS experiments on monoclonal antibodies and recombinant proteins to assess sequence coverage and sites of modification
- Participate in IND, IMPD, BLA, and other regulatory filings
- Develop test methods, provide documentation and write scientific reports.
- Conduct testing to support analytical development, manufacturing process development, process validations, and manufacturing investigations
- Lead or facilitate technical discussions and participate in cross-functional teams at project-related meetings
Qualifications
Education:
- A Ph.D. in chemistry, biochemistry or a related field with 0~2 years of proven experience, or demonstrated ability is required
Experience and Skills:
Required:
- Hands-on experience with LC-MS is required
Preferred:
- Proficiency at running and trouble-shooting assays is preferred
- Experience maintaining high quality documentation, analyzing and accurately interpreting data, and preparing reports, and SOPs is preferred
- Strong written and verbal communication and excellent interpersonal skills is preferred
- An understanding and experience in the application of various GXP concepts is preferred
Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.
For more information on how we support the whole health of our employees throughout their wellness, career and life journey, please visit www.careers.jnj.com