Johnson & Johnson (J&J) is recruiting for a Senior Scientist, Neuropsychiatry to join our Neuroscience Discovery group based in San Diego, CA, USA.

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com/.

The successful candidate will actively engage in early discovery efforts to support Johnson & Johnson's Neuropsychiatry discovery strategy. The candidate will perform cellular, biochemical and molecular biology experiments for understanding the function of new targets and their involvement in signaling pathways related to disease pathology, and use relevant cell lines, primary cell cultures, tissue slices and induced pluripotent stem cells. They will be responsible for the planning and hands-on execution of studies related to validation of new targets, and oversee all aspects of the generation, analysis and accurate recording of data in compliance with data integrity requirements and interpret and effectively present the findings to the project team. These efforts will help reveal underlying mechanistic disease biology and aid the development of novel disease-modifying therapies as well as in the validation of potential new drug targets for the treatment of neuropsychiatric disorders.

• Design, perform and interpret biochemical, cell and molecular biology experiments, troubleshoot and refine experimental protocols, to support target discovery and validation activities for Neuropsychiatry.
• Design and conduct in vitro cell biology studies to understand target biology and validate novel targets using genetic and/or chemical biology approaches.
• Collaborate with computational scientists, biologists, and vendors and work within an extended team environment to support progress towards the project and team goals.
• Prepare and record experimental reports that include detailed methods and materials, raw data, data analyses and graphs, and conclusions in the electronic laboratory notebook.
• Follow laboratory safety and data integrity guidelines.
• Present experimental results during group and project team meetings, and to internal and external scientific community through presentations and publications.

• a PhD degree with 0-3 years postdoctoral experience OR a Master's degree with 8+ years of experience OR a Bachelor's degree with 12+ years of experience in Biochemistry, Neuroscience, Molecular Biology or a similar field is required.

• 5+ years of hands-on experience in mammalian cell cultures including cell model generation and assay development.
• Broad experience in cell and molecular biology, and biochemical techniques, such as gene over-expression/knockdown for target validation, immunofluorescence staining, microscopy, Western blotting and RT-PCR.
• Solid planning and organizational skills with a meticulous nature.
• This individual must be a highly collaborative scientist who will be comfortable in both an individual contributor role and as part of a multidisciplinary research team.
• High motivation to contribute to research efforts to improve outcomes for patients suffering from psychiatric diseases is required.

• Expertise in evaluating signal transduction pathways is highly preferred.
• Experience in functional genomics techniques is preferred.
• Demonstrated previous work with in vitro models of brain disorders would be highly advantageous.

• Employees and/or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance.
• Employees may be eligible to participate in the Company's consolidated retirement plan (pension) and savings plan (401(k)).
• This position is eligible to participate in the Company's long-term incentive program.
• Employees are eligible for the following time off benefits:
• Vacation - up to 120 hours per calendar year
• Sick time - up to 40 hours per calendar year; for employees who reside in the State of Washington - up to 56 hours per calendar year
• Holiday pay, including Floating Holidays - up to 13 days per calendar year of Work, Personal and Family Time - up to 40 hours per calendar year
• Additional information can be found through the link below. https://www.careers.jnj.com/employee-benefits