Johnson & Johnson is recruiting for a Senior Scientist, Downstream Processing to be located in Malvern, PA.
At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com/.
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This position will lead and perform purification process development for the antibody-based modalities within the API-Large Molecule group in Malvern, PA. Primary responsibilities will include leading and participating in the design of experiments, executing the planned experiments, and optimizing the process steps to the target process scale. This will include laboratory and occasional pilot-scale scale chromatography and filtration. The candidate will lead the design and execution of development studies to identify and determine appropriate conditions and ranges of (critical) process parameters for chromatographic purification and separation and several types of filtration. The candidate will record and analyze experimental data, verify data integrity and accuracy, interpret analytical characterization results, and report/summarize findings to the project team, and also draft technical documents and perform technology transfer to collaboration partners. The candidate should have experience with computational modeling/simulations and knowledge of downstream application. The candidate is expected to work in a team environment as well as contributing individually to meet project timeline and objectives.
Key Responsibilities:
- Lead and perform process development for the antibody purification processes.
- Lead, design and execute planned experiments which will include laboratory and occasional pilot-scale chromatography and filtration.
- Lead, design and execute development studies to identify and determine appropriate conditions and ranges of (critical) process parameters for chromatographic purification & separation and several types of filtration.
- Record, analyze and present data to project teams.
Qualifications
Education:
- Minimum of a MS Degree in Chemical/Biochemical Engineering or Biochemistry or related field with a minimum of 7 years of experience is required. PhD in Chemical/Biochemical Engineering or Biochemistry or related field with a minimum of 0-5 years of relevant post-doctoral experience is preferred.
Experience and Skills:
Required:
- Knowledge and hands-on experience in downstream processing and purification of antibodies and/or antibody-based products, in particular chromatography and filtration.
- Must be highly organized and capable of leading/pursuing multiple projects with some supervision.
- Good written and verbal communication skills.
- Experience maintaining written records of work in the form of (electronic) notebooks, technical reports, and protocols.
- Data reporting, ability to present findings to management, and experience with team-based collaborations.
- Occasional weekend work is required as well as occasional travel in support of manufacturing.
Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.
For more information on how we support the whole health of our employees throughout their wellness, career and life journey, please visit www.careers.jnj.com.