Johnson & Johnson Innovative Medicine is recruiting for a Senior Scientist, CRC Discovery, located in Spring House, PA.
At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com/.
For more than 130 years, diversity, equity & inclusion (DEI) has been a part of our cultural fabric at Johnson & Johnson and woven into how we do business every day. Rooted in Our Credo, the values of DEI fuel our pursuit to create a healthier, more equitable world. Our diverse workforce and culture of belonging accelerate innovation to solve the world's most pressing healthcare challenges. We know that the success of our business - and our ability to deliver meaningful solutions - depends on how well we understand and meet the diverse needs of the communities we serve. Which is why we foster a culture of inclusion and belonging where all perspectives, abilities and experiences are valued and our people can reach their potential. At Johnson & Johnson, we all belong.
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The successful candidate will join the Colorectal Cancer Discovery team to advance innovative drug candidates for the treatment of cancer. They will work in a dynamic environment across the different stages of preclinical drug discovery on projects that include the design, execution and interpretation of studies for the validation and characterization of therapeutic agents and new targets. We seek a highly motivated and dedicated individual with an outstanding scientific track record who will be organized, work well in a team setting, show leadership, and be sensitive to timelines. Experience in solid tumor drug discovery is preferred. Troubleshooting skills are crucial. They will efficiently collaborate with colleagues in the oncology as well as in the small molecule and biotherapeutic discovery organization, and present scientific results to multidisciplinary teams.
Key Responsibilities:
- Design, perform, troubleshoot, interpret and report laboratory experiments to characterize drug candidates and to identify and validate novel targets and therapeutic concepts.
- Manage multiple experiments and projects simultaneously while engaging with partner functions.
- Prepare, review, and present materials to support internal governance decisions, regulatory filings, publications, and commercial interactions.
- Monitor scientific and patent literature relevant to areas of responsibility.
Qualifications
Education:
- Ph.D. or equivalent experience in a relevant discipline with post-doctoral experience, 1+ years of industry experience in a biotech or pharmaceutical environment, and a strong record of publications and/or patents is required.
Qualifications
Required:
- Experience in Oncology Discovery is required.
- Outstanding tissue culture proficiency is required.
- Experience in assay development, optimization and troubleshooting is required.
- Hands-on experience in performing assays to characterize small molecules, large molecules, T cell engagers, and/or antibody-drug conjugates is required.
- Knowledge of statistical methods vital for the interpretation of preclinical studies and experience with software for generating publication-ready figures (e.g., PRISM) are required.
Preferred:
- Hands-on experience with CTG assays, IncuCyte assays, Western blotting, co-culture assays, multi-color flow cytometry, immunofluorescence, siRNA/CRISPR perturbations, qRT-PCR, and use of liquid handling robotics is preferred.
- Hands-on experience in characterizing the PK/PD profiles of experimental therapies is preferred.
- Experience in colorectal cancer research is preferred.
- Experience working in cross-functional teams is preferred.
- Knowledge of the clinical and commercial landscapes in colorectal cancer is preferred.
The anticipated base pay range for this position is $104,000. to $166,750.
Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.
For more information on how we support the whole health of our employees throughout their wellness, career and life journey, please visit www.careers.jnj.com.]