Senior Principal Scientist, Omics

For more than 130 years, diversity, equity & inclusion (DEI) has been a part of our cultural fabric at Johnson & Johnson and woven into how we do business every day. Rooted in Our Credo, the values of DEI fuel our pursuit to create a healthier, more equitable world. Our diverse workforce and culture of belonging accelerate innovation to solve the world's most pressing healthcare challenges.

We know that the success of our business - and our ability to deliver meaningful solutions - depends on how well we understand and meet the diverse needs of the communities we serve. Which is why we foster a culture of inclusion and belonging where all perspectives, abilities and experiences are valued and our people can reach their potential.

At Johnson & Johnson, we all belong.

We are seeking an innovative and collaborative Senior Principal Scientist to join the Discovery Omics team, who will be responsible for applying high-dimensional biology throughout the drug discovery process, including understanding the mode of action of compounds, assessing off-target effects, and facilitating reverse translation. This individual will demonstrate a deep understanding of omics technologies and strong computational biology skills, with a focus on the analysis and interpretation of omics data. Utilize knowledge of genetics and pathway biology is essential to address the needs and scientific questions posed by collaborating teams and to assist in interpreting experimental findings. This role will support global teams across various therapeutic areas.

Principal Responsibilities:

• Lead discovery omics projects in collaboration with functional and therapeutic area partners across multiple therapeutic modalities.
• Develop and implement (multi-)omics data analysis plans to support target identification and validation, lead optimization, and liability assessments.
• Collaborate with wet lab and computational teams to define the required analysis plan to achieve project goals.
• Drive internal and external innovation projects.

Qualifications

• A minimum of a Ph.D. in Biology, Biotechnology, Immunology, or a related discipline is required.
• A minimum of 3 years of relevant pharmaceutical industry experience is required.
• Prior experience in drug discovery is required.
• Established knowledge/focus in computational biology, supported by relevant publications is preferred.
• Proficiency in programming languages, such as R and/or Python, is required.
• Strong expertise in standard transcriptomics data analysis (data processing, differential gene expression, pathway analysis) is preferred.
• Strong expertise in data visualization tools and methodologies is preferred.
• Knowledge of machine learning algorithms is preferred.
• Knowledge of statistical modeling is preferred.
• Knowledge of unsupervised analysis techniques preferred.
• Experience with multi-omics data integration is preferred.
• Familiarity with large language models and generative methods is preferred.
• Experience working within Amazon Web Services (AWS) is preferred.
• Must have strong written and verbal communication and interpersonal skills.
• Must be independent, self-motivated, and possess an innovative mindset.
• Must have a strong team orientation and be highly collaborative and results-driven with the ability to work productively in a dynamic environment.
• The ability to translate and convey complex information and concepts to scientists from diverse backgrounds is required
• The ability to collaborate effectively with all levels in matrix environment is required.

The anticipated base pay range for this position in all other U.S. locations is $137,000 to $235,750.

The Company maintains highly competitive, performance-based compensation programs. Under current guidelines, this position is eligible for an annual performance bonus in accordance with the terms of the applicable plan. The annual performance bonus is a cash bonus intended to provide an incentive to achieve annual targeted results by rewarding for individual and the corporation's performance over a calendar/ performance year. Bonuses are awarded at the Company's discretion on an individual basis.

Employees and/or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance.

Employees may be eligible to participate in the Company's consolidated retirement plan (pension) and savings plan (401(k)).

Employees are eligible for the following time off benefits:

• Vacation - up to 120 hours per calendar year
• Sick time - up to 40 hours per calendar year; for employees who reside in the State of Washington - up to 56 hours per calendar year
• Holiday pay, including Floating Holidays - up to 13 days per calendar year
• Work, Personal and Family Time - up to 40 hours per calendar year

For additional general information on company benefits, please go to: https://www.careers.jnj.com/employee-benefits

The compensation and benefits information set forth in this posting applies to candidates hired in the United States. Candidates hired outside the United States will be eligible for compensation and benefits in accordance with their local market.

This job posting is anticipated to close on February 17, 2025. The Company may however extend this time-period, in which case the posting will remain available on https://www.careers.jnj.com to accept additional applications.

Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.