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RNA Therapeutics and Delivery is an organization within Therapeutics Discovery, committed to the delivery of high-quality drug candidates in the novel synthetic modalities space working closely with Johnson & Johnson Innovative Medicines Therapeutic Areas (TA) discovery teams. Our mission requires critical thinking, a portfolio approach and deep scientific expertise in several fields including oligonucleotide chemistry, bioconjugation chemistry, nanotechnology, cellular and molecular pharmacology and screening technologies coupled with an ability to work collaboratively with internal and external partners. This role offers growth opportunity within a dynamic and science driven organization.

Key Responsibilities:

• Support the synthesis of oligonucleotides and bioconjugates for delivery.
• In collaboration with the team, support oligonucleotide innovation, optimization and process development efforts.
• Support the optimization of chemistry processes for solid phase synthesis, purification, analysis of oligonucleotides and bioconjugates under limited supervision.
• Evaluate experiment data and communicate scientific findings as verbal presentations and written reports.

Qualifications

Required:

• B.S. or MS. in organic/medicinal chemistry, chemical biology, or related field with 1 - 3 years of industry or academic experience in oligonucleotide drug discovery
• Experience in phosphoramidite synthesis, purification, and analytical characterization
• Exposure to the oligonucleotide drug discovery process
• Critical thinking and scientific skills and a consistent record to interpret and clearly communicate data
• Strong standout colleague with the ability to work optimally in a dynamic matrix team environment with diverse views
• Ability to adapt to changing priorities and timelines

Preferred Qualifications:

• Experience with an emphasis on nucleic acid chemistry
• Proven record of accomplishments in oligonucleotide research in the form of patents, publications and/or presentations at major national meetings
• Knowledge and experience with delivery of oligonucleotides using bioconjugation strategies
• Solid understanding of RNA biology and oligonucleotide screening technologies to facilitate effective teamwork

The anticipated base pay range for this position is $74,000- $119,600 USD. The base salary range listed is based on a US pay scale and may be adjusted based on the successful candidate's geographic location

The Company maintains highly competitive, performance-based compensation programs. Under current guidelines, this position is eligible for an annual performance bonus in accordance with the terms of the applicable plan. The annual performance bonus is a cash bonus intended to provide an incentive to achieve annual targeted results by rewarding for individual and the corporation's performance over a calendar/performance year. Bonuses are awarded at the Company's discretion on an individual basis.

Employees and/or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance.

Employees may be eligible to participate in the Company's consolidated retirement plan (pension) and savings plan (401(k)).

Employees are eligible for the following time off benefits:

• Vacation - up to 120 hours per calendar year
• Sick time - up to 40 hours per calendar year
• Holiday pay, including Floating Holidays - up to 13 days per calendar year
• Work, Personal, and Family Time - up to 40 hours per calendar year

Additional information can be found through the link below. For additional general information on Company benefits, please go to: https://www.careers.jnj.com/employee-benefits.

This job posting is anticipated to close on November 18, 2024. The Company may however extend this time-period, in which case the posting will remain available on https://www.careers.jnj.com to accept additional applications.

Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

For more information on how we support the whole health of our employees throughout their wellness, career and life journey, please visit www.careers.jnj.com.